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This must be a frightening time for both of you. It was Chandi who told me about this website. As to the herceptin, 4mg/kg is a loading dose and only happens in the beginning. Herceptin can be given weekly or 3 weekly whatever works best with any complimentary chemo. I was on herceptin 3 weekly alone, then went to weekly when I was given weekly taxotere for lung mets. Each time you change the regime or more than the allotted time passes (1 wk or 3 wks) you need a new loading dose. As to when to start this- I don't think a week delay would make much difference. If you have good faith in your onc, trust their advice.
Blessings, Elisabeth
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