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I've had swollen ankles from herceptin since I began receiving it last summer. I get my heart cked with a Muga every so often and it's been ok so far. Herceptin is known for its effect on the heart. It doesn't happen every wk now and it's not as dramatic as it once was, but I agree with Lolly in that you shd mention to your onc. Elevating your legs/feet above your heart might help....I like to get on the sofa and prop my legs up on the back. Good luck!
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