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When it rains it pours. I had my SRS while on gemzar but what we did is held the dose a week before and a week after. The dose was also reduced by 20% after the rads.
Gemzar is one of the most radiosensitizing chemos available and I was very nervous about it. I did a medline search and found a guy in Texas who has written numerous articles on this and he was the one who suggested holding the dose the week before and after. If you like, I can try and find his e mail but I am not sure if I kept it.
Has Cindy been on navelbine? Xeloda?
There have been a few promising studies about xeloda and brain mets. Apparently, xeloda does seem to cross the blood brain barrier to some degree and there have been a few cases of complete responses in the brain to xeloda. During radiation, the blood brain barrier is leaky so this is an ideal time to take it as well. I remained on my xeloda during my rads without any problem. ( I am on gemzar and xeloda combo )
Hang in there, Ron and Cyndi. We are all behind you!
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