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I see - so they may want to BEGIN the herceptin with the other drug at the same time in a trial. A decision like that should be made ASAP, and not wait for these mets to take hold any farther! The sooner she gets on treatment, the better for her peace of mind, for Heaven's sake.
My med onc started me in a trial IMMEDIATELY for hard-to-treat mets. This trial worked for me and was for women either with or without herceptin. The main trial drugs were Navelbine and Taxol.
Personally, I would leave Iressa for later, if I needed it. Go with what has worked for so many and is available NOW.
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