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I was on Temodar for 18 mos.. I had a reoccurrance while on Temodar. My Dr. told me that brain tumors do a lot better on it than brain mets. He sees pts. who have had glioblastnoma living 2 years out and counting (verses 7 mos. on average prior to Temodar) but with brain mets studies have shown it is not as effective just a few additional mos. about 2-3. I took it with Zofran so the side effects were not so bad. Some times I would just throw up but you get sick and you are fine again. I would feel good 95% of the time.
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