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I started on navelbine/herceptin wkly, with zometa monthly, in July, 2003, for mets to bones and skin. Navelbine quit working in Jan 04 and I switched to gemzar in Feb 04. Developed brain mets this summer and had gamma knife. I also had a lot of trouble with fatigue this summer and skipped some chemo treatments, then began a program of every 2 wks. Too early to assess the effect, but I feel a lot better, so I hope there are no problems. Good luck to you!
Love, Jackie
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