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HI lindaw;
I have 3 liver mets and it does appear to be working, accoriidng to my ct scan they had shrunk by half after the 3 cycle (2 weeks on 1 week off). I did not start to have really bad itching until after the 3rd cycle, and have not had any problems on the bottoms of my hands and feet. I just finished my 6th cycle and have more scans next week.
In my live person support group, 3 other people have recently started xeloda at doses between 3500 and 4000 mg/day. None of them could tolerate it after two weeks and had bad rashes, and hand/foot problems. I told my onc about them and when he next saw the drug rep he ask them about the higher doses. The rep said that he hears most people can not tolerate above 3000 without significant side effect. The standard dose is 2500.
kk
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