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Every one I know with brain mets got that after other distant spread. Sometimes taking 4-6 years after original treatment to rear their ugly head. Most were successfully treated. I have one friend who passed away as her brain mets came with too many other areas in her body affected and all the treatments coudn't stop the spread. It was very sad as she was a lovely woman in every way. One of those odd cases where the same drugs for organ mets worked for me and not her. I say this with a tear in my eye ...
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