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I was experiencing something similar to you in Feb of this year when I was initially starting on Xeloda.
My husband and I enjoy being active, snow skiing, water skiing, traveling, etc. so being able to be active was important to me.
Afer discussing it with my oncologist, we reduced the dosage a bit, and I've been fine ever since.
It hasn't seemed to have affected treatment outcome, either, as I'm now NED in the bone mets, and the liver mets are over 50% gone after 8 months of treament.
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