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my understanding is that adria plus cytoxan is still the first line of treatment for a her2neu positive breast cancer, but that NOW they add a taxane to it, so that you would have four a/c treatments followed by four taxane treatments (possibly given in 12 once per week intervalsa). the addition of herceptin to the mix is a wonderful "insurance" policy - no guarantee, but helpful possibly, no one knows how helpful, but who cares, since it is relatively nontoxic, althoug there IS a risk of heart damage, which an occasional echo can rule out.
my advice is to GO with the therapy recommended to you PLUS the addition of a taxane PLUS, if possible the addition of a year of herceptin. It is what I would have pushed for if I were stage I (I was stage II, so it was easier for me to get all of that stuff).
Since you are hormone negative, you HAVE not other treatments up your sleeve - I would push for the most aggressive NOW., in the adjuvant setting.
lauren
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