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Rick,
My first Navelbine/Herceptin infusion caused me quite a lot of pain in my chest and left shoulder blade and left arm( as far as scans and biopsy could tell I was only dealing with mets to lymph nodes and skin on left side). It subsided as the treatment continued, and the following week's infusion went much easier; by the third infusion I had a port and also no more pain. I don't think there's any way to get around the fatigue, it comes with the territory, she could see about shots to help the blood recover more quickly, but otherwise just get lots of rest and pace herself.
Best Wishes to you both,
Lolly
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