HER2 Support Group Forums - View Single Post - Intrathecal (IT) Herceptin (Trastuzumab) for brain mets (Leptomeningeal Metastases)

marvass · 11-17-2016, 06:28 AM

Carol is still with mets
7 months ago she was locally irradiated for 3 mets measuring 12,12, and 7 mm. She continued doing IT herceptin at 250mg every 10 or 11 days till today.

In the first 3 months the mets shrunk to 6,7, and 3 mm. But an MRI last week showed that these have grown up to 13,13 and 8mm.

So today is the last IT herceptin that she is doing. We will start 1250mg/day tykerb and 130mg taxol per week as from today. She can still walk with some help, steroids are at 1mg/day, and still taking IV herceptin at 6mg/kilo.

We will do 6 weeks like this and then do another MRI.

11-17-2016, 06:28 AM	#214
marvass Senior Member Join Date: May 2012 Posts: 105	Re: Intrathecal (IT) Herceptin (Trastuzumab) for brain mets (Leptomeningeal Metastase Carol is still with mets 7 months ago she was locally irradiated for 3 mets measuring 12,12, and 7 mm. She continued doing IT herceptin at 250mg every 10 or 11 days till today. In the first 3 months the mets shrunk to 6,7, and 3 mm. But an MRI last week showed that these have grown up to 13,13 and 8mm. So today is the last IT herceptin that she is doing. We will start 1250mg/day tykerb and 130mg taxol per week as from today. She can still walk with some help, steroids are at 1mg/day, and still taking IV herceptin at 6mg/kilo. We will do 6 weeks like this and then do another MRI.