HER2 Support Group Forums - View Single Post - Resistance of ER-positive breast cancer to tamoxifen therapy may be driven by APOBEC3

News · 12-10-2015, 10:30 AM

Responses to tamoxifen were significantly prolonged by reducing levels of the enzyme APOBEC3B in preclinical models of estrogen receptor-positive breast cancer and significantly shortened by...

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12-10-2015, 10:30 AM	#1
News Senior Member Join Date: Oct 2007 Posts: 20,133	Resistance of ER-positive breast cancer to tamoxifen therapy may be driven by APOBEC3 Responses to tamoxifen were significantly prolonged by reducing levels of the enzyme APOBEC3B in preclinical models of estrogen receptor-positive breast cancer and significantly shortened by... More...