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				Re: Significant Progression-Going On Doxil
			 
 Karen, I am still hoping that this means your treatment is starting to work. When I started TDM1 my CA15.3 and ACE kept going up but the scan showed a big improvement. The markers went down just after. There was a kind of a flare phenomenon. I keep my fingers crossed hoping that it is what is happening. Hugs. Michka 
				__________________08.2006 3 cm IDC Stage 2-3, HER2 3+ ER+90% PR 20%
 FEC, Taxol+ Herceptin, Mastectomy, Radiation, Herceptin 1 year followed by Tykerb 1 year,Aromasin /Faslodex
 
 12.2010 Mets to liver,Herceptin+Tykerb
 03.2011 Liver resection ER+70% PR-
 04.2011 Herceptin+Navelbine+750mg Tykerb
 06.2011 Liver ned, Met to sternum. Added Zometa 09.2011 Cyberknife for sternum
 11.2011 Pet clear. Stop Navelbine,  continuing on Hercpetin+Tykerb+Aromasin
 02.2012 Mets to lungs, nodes, liver
 04.2012 TDM1, Ned in 07.2012
 04.2015 Stop TDM1/Kadcyla, still Ned, liver problems
 04.2016 Liver mets. Back on Kadcyla
 08.2016 Kadcyla stopped working. mets to liver lungs bones
 09.2016 Biopsy to liver. no more HER2, still ER+
 09.2016 CMF Afinitor/Aromasin/ Xgeva.Met to eye muscle Cyberknife
 01.2017 Gemzar/Carboplatin/ Ibrance/Faslodex then Taxotere
 02.2017 30 micro mets to brain breathing getting worse and worse
 04.2017 Liquid biopsy/CTC  indicates HER2 again. Start Herceptin with Halaven
 06.2017 all tumors shrunk 60% . more micro mets to brain (1mm mets) no symptoms
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