Re: Kadcydla versus neurosurgery and paralysis
Topotecan used with the Herceptin IT did not work for my daughter. The area became larger and the spinal fluid cells showed contamination.
They started Depocyt - a really fierce chemo that was given every three weeks IT and the other weeks in between she received the 80 mg Herceptin IT. Her neuro affects became worse for a while and she had to have dexamethasone but it took down the growth.
They have stopped the Depocyt now and she is just on the Herceptin IT for the leptomeningeal problem.
Of course she had to do the Abraxine for the lymph nodes that Kadcyla and other prior targeted drugs were not working to take down.
I don't know it the Depocyt would do the job for you or that your insurance would approve. It is a fierce drug and made her pretty sick for a while, but worked to take the tumor down and the Emend stopped the nausea and vomiting.
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