Thank you once again for another fascinating article. At the suggestion of my surgeon, I had the Ambry Genetics Breast Next gene profile done. I came out negative across the board. While most of this genetic stuff is still a mystery to me, this article helps me put a piece of my puzzle together. I don't have a p53 mutation. I'm going to take this as a good thing for now. However, I do see that it would make this new research not something that might work for me should I need it.
For anyone interested, this panel tests
ATM, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CHEK2, MRE11A, MUTYH, NBN, NF1, PALB2, PTEN, RAD50, RAD51C, RAD51D, STK11 and
TP53. link