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phil · 11-06-2013, 02:25 PM

sounds like your dau has tried a lot. addition of a taxane or herc/ tykerb might be an option. i'm surprised she didnt get taxotere w/ herc/perjeta. taxanes are tough , but so is xeloda, navelbine for some, adria , etc. some docs might give a taxane at a lower dose or give a week off schedule. it may not be needed for too long . my wife went back to adria , so nasty, to bridge the wait for tdm-1. which has been her miracle .
i heard about a promising early stage trial for her2 at farber. using t dm-1 technology to attach several HER antibodies to a dose of doxil. targeted chemo so hopefully fewer s/e. definitely interesting for those who progress on t dm-1 or perjeta. maybe that trial is at other research hospitals .

11-06-2013, 02:25 PM	#15
phil Senior Member Join Date: Nov 2010 Posts: 393	Re: Anything new that targets Her2 neu? sounds like your dau has tried a lot. addition of a taxane or herc/ tykerb might be an option. i'm surprised she didnt get taxotere w/ herc/perjeta. taxanes are tough , but so is xeloda, navelbine for some, adria , etc. some docs might give a taxane at a lower dose or give a week off schedule. it may not be needed for too long . my wife went back to adria , so nasty, to bridge the wait for tdm-1. which has been her miracle . i heard about a promising early stage trial for her2 at farber. using t dm-1 technology to attach several HER antibodies to a dose of doxil. targeted chemo so hopefully fewer s/e. definitely interesting for those who progress on t dm-1 or perjeta. maybe that trial is at other research hospitals .