10-25-2013, 10:43 AM
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#20
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Senior Member
Join Date: Apr 2008
Location: Sunny San Diego
Posts: 2,214
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Re: Pattern of recurrence of early bc differs by intrinsic subtype & proliferation in
If you look at page 12 under: Analysis of recurrence prognostic factors and variations in recurrence risk over time
Quote:
For the HER2-enriched subtype, the first peak occurred at approximately the same time, nearly 20 months for both groups, but the maximum risk was 1.0% (95% CI: 0.5%-2%) in patients with Ki-67 <14% and 1.3% (95% CI: 0.9%-3.1%) in those cases with Ki-67 ≥14%. A second risk peak at 72 months appears for both HER2 populations, but interestingly the magnitude in this case seems to be higher in the HER2-enriched with Ki-67 <14% (0.75%; 95% CI: 0.3%-1.8%) than with Ki-67 ≥14%
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Here they state for both Her2 populations there is a peak at 72 months and it was higher for the lower KI67 scores.
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