I have had acrylic nails for 20 years. I, very sadly, removed them between my first and second chemo treatments. I did everything I could to keep my nails healthy and strong throughout my chemo time. I was very careful with them. However, my nails got infected and some even bleed. I was grateful that I didn't have the acrylics on at the time. The infection wasn't caused by any clipping or filing I did on my nails. I just had a very weird reaction to Taxotere. No one knows how our bodies will reaction to chemo. I had no problems with my nails until AFTER my last TCH treatment. I think you should do whatever you can to mitigate any problems. You can always put the acrylic back on when you're done if you don't have issues.
As a side note - I am actually liking the very short and painted look of my nails right now. I'm not sure if I'll put the acrylic back on or not....
Jeri