HER2 Support Group Forums - View Single Post - IT herceptin for brain mets only??

This is the reply that I got back from a clinical trials guy:
For LM disease it can be seen sometimes on MRI’s or if a spinal tap is done. It is not clear that giving it into the spinal fluid would allow it to penetrate into the brain to be of value.

I am unaware of anyone.

Sorry.

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Feb 2013 - NED
Mar 2013 - thought I had progression, watching brain.
April 2013 - GOT MARRIED!!!!
May 2013 - looks like no progression, but necrosis and bigger.
Oct-Dec 2013 - Avastin tx
Nov 2013 - MRI shows necrosis shrinkage!!!!
Jan 2014 - Lepto Mening. disease found
Feb 2014 - WBR
March - BLAHHHH
April 2014 - Liver mets found
April 2014 to present - Chemo again, whooohoo. Fun!
July 2014, scans look good.
Stay on Perjetand hercertin.
Nov. 2014 more lepto-mening disease more WBR.
Feb 2015 more lepto-mening disease in spine and neck. More radiation.
Start on TDM1 no more Perjeta stay on herceptin
March 2015 more radiation in my thoracic area, more lepto-meningial disease
April 2015 trying to walk again.
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04-22-2013, 08:27 AM	#7
dearjilly Senior Member Join Date: Feb 2012 Location: Ontario, Canada Posts: 115	Re: IT herceptin for brain mets only?? This is the reply that I got back from a clinical trials guy: For LM disease it can be seen sometimes on MRI’s or if a spinal tap is done. It is not clear that giving it into the spinal fluid would allow it to penetrate into the brain to be of value. I am unaware of anyone. Sorry. __________________ [ Feb 2013 - NED Mar 2013 - thought I had progression, watching brain. April 2013 - GOT MARRIED!!!! May 2013 - looks like no progression, but necrosis and bigger. Oct-Dec 2013 - Avastin tx Nov 2013 - MRI shows necrosis shrinkage!!!! Jan 2014 - Lepto Mening. disease found Feb 2014 - WBR March - BLAHHHH April 2014 - Liver mets found April 2014 to present - Chemo again, whooohoo. Fun! July 2014, scans look good. Stay on Perjetand hercertin. Nov. 2014 more lepto-mening disease more WBR. Feb 2015 more lepto-mening disease in spine and neck. More radiation. Start on TDM1 no more Perjeta stay on herceptin March 2015 more radiation in my thoracic area, more lepto-meningial disease April 2015 trying to walk again. [/SIZE][/FONT]