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Sdgirl · 04-13-2013, 08:12 AM

An update on me. I have been taking tykerb and TDM1 together for three weeks now. I have increased diarrhea and nausea and also feel more tired. Also have pimples like rash on skin. I had tumor markers done on Friday. Do not have results yet and will find out if this combination is working. I also have a brain MRI in two weeks. We added Tykerb since we think TDMI on its own may have stopped working as my tumor markers doubled even though I had good scans. The combination is doable but is much harder than doing TDM1 alone. I expected that but what choice do we have. Just have to suck it in and carry on with the diarrhea, nausea, fatigue. My liver enzymes had also gone by 10 points yesterday. I take 5 pills everyday. Hopefully it is because of tykerb and not my liver mets. I will update once I find out my tumor markers. Fingers crossed.

04-13-2013, 08:12 AM	#15
Sdgirl Senior Member Join Date: Jun 2012 Location: San Diego Posts: 33	Re: Tdm1/kadcyla and Tykerb An update on me. I have been taking tykerb and TDM1 together for three weeks now. I have increased diarrhea and nausea and also feel more tired. Also have pimples like rash on skin. I had tumor markers done on Friday. Do not have results yet and will find out if this combination is working. I also have a brain MRI in two weeks. We added Tykerb since we think TDMI on its own may have stopped working as my tumor markers doubled even though I had good scans. The combination is doable but is much harder than doing TDM1 alone. I expected that but what choice do we have. Just have to suck it in and carry on with the diarrhea, nausea, fatigue. My liver enzymes had also gone by 10 points yesterday. I take 5 pills everyday. Hopefully it is because of tykerb and not my liver mets. I will update once I find out my tumor markers. Fingers crossed.