HER2 Support Group Forums - View Single Post - combining an NFKappa-beta inhibitor with metformin seems a "dynamic duo" vs. cancer

zoco · 03-31-2013, 04:49 PM

Hi anyone tried this?
It actually can work only if ONLY ALL 3 THING ARE COMBINED:
KETOGENICDIET + METF + NFKB inhibitors. If NFKB missing cnc switches to fat burning, if Metf missing, liver makes glucose from lactic acid. So all 3 must go together.
I guess 4 weeks course could make some interesting results, 8 would be best:
0.week- allow normal sugar diet to get cnc cells adapted to glucose
1.week- 1st half of weekNFKB inhibitors, 2nd half of week: start Keto.d.
2-3-4week: add metformin.
The more weeks, perhaps the better.
Ketogenic diet-use urine test strips to see if body is in ketosis - violet colour typically in respective test square. Only this is real ketosis. Otherwise you are ketting some sugar from diet in maybe you are not aware of (eg. Milk, ...). Coconut oil or MCT oil is base for Ketogenic diet. Allow more calories intake that out so you dont loose weight.
Worth a try..

interesting, related:
Unexpected Antitumorigenic Effect of Fenbendazole when Combined with Supplementary Vitamins-http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687140/

the mechanism in this study is same, but Fenbendazole antiworm drug makes similar effect like Keto.d.&Metf - it block glucose update of cells - its like artificial ketosis.
And in this study they accidentally discovered the same mechanism - block the NFKB switch by vitamins (A,C,E,...) and glucose and cnc cell cannot switch to alternative sources of energy..

03-31-2013, 04:49 PM	#7
zoco Junior Member Join Date: Dec 2012 Posts: 2	Re: combining an NFKappa-beta inhibitor with metformin seems a "dynamic duo" vs. canc Hi anyone tried this? It actually can work only if ONLY ALL 3 THING ARE COMBINED: KETOGENICDIET + METF + NFKB inhibitors. If NFKB missing cnc switches to fat burning, if Metf missing, liver makes glucose from lactic acid. So all 3 must go together. I guess 4 weeks course could make some interesting results, 8 would be best: 0.week- allow normal sugar diet to get cnc cells adapted to glucose 1.week- 1st half of weekNFKB inhibitors, 2nd half of week: start Keto.d. 2-3-4week: add metformin. The more weeks, perhaps the better. Ketogenic diet-use urine test strips to see if body is in ketosis - violet colour typically in respective test square. Only this is real ketosis. Otherwise you are ketting some sugar from diet in maybe you are not aware of (eg. Milk, ...). Coconut oil or MCT oil is base for Ketogenic diet. Allow more calories intake that out so you dont loose weight. Worth a try.. interesting, related: Unexpected Antitumorigenic Effect of Fenbendazole when Combined with Supplementary Vitamins-http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687140/ the mechanism in this study is same, but Fenbendazole antiworm drug makes similar effect like Keto.d.&Metf - it block glucose update of cells - its like artificial ketosis. And in this study they accidentally discovered the same mechanism - block the NFKB switch by vitamins (A,C,E,...) and glucose and cnc cell cannot switch to alternative sources of energy..