[phil]

right you are chrisy, many prior toxic therapies that you, Lorraine and others here are very familiar with. None of the top FDA officials are familiar with them in any real sense. thats the problem. the researchers say it will ' revolutionize " the tx of her2 , but This FDA will hold it back, and thousands more will die. when will perjeta ever get to stage iv pts ? when will t dm-1 ever get to people like Lorraine was in 2006, with one visible tumor, not 7. she was lucky to have it go only to liver area, and to get aggressive , state of the art tx to stay alive. Stephn, i have heard from many who have yrs , 1, 2, 3 and 4 yrs. many who get good results in trials don't know how lucky they are. and there are so few when you crunch the numbers. for ex., we ran into a pt when we started in va., over ayr ned , she didnt know anything about t dm-1. she lived down the road , and her doc sent her to the clinic. the current trial system is slow, and small no's . my estimate is probably Gen. has given t dm-1 to less than 2,000 pts total , and with a 60% or so success rate , thats about 1,000 , many of them new, getting it only in past yr in expanded EMILIA, THERESA. when we were trying to get it in 2010, 3 + yrs into trials, there was only one trial at Farber, and it took a new pt once very month or so. pathetic. overall t dm-1 enrollment is a pathetically low no. for over 6 yrs of testing. but typical of trials in US. in the 6th decade of the " war " on cancer. in the 21st century . yet 240,000 will be dx this yr, 40,000 will die . got to get it to the early stage folks. got to keep Protesting . its past time to " Fix This FDA "