HER2 Support Group Forums - View Single Post - Intrathecal (IT) Herceptin (Trastuzumab) for brain mets (Leptomeningeal Metastases)

marvass · 02-15-2013, 10:14 AM

But Carol's dose went up very quickly, if i remember correctly with the 14th dose we were already at 100mg, and MRI still showed more new spots inside the brain on the 2nd MRI after the 14th dose, then went to 150mg and after 22 weeks it just settled. With 40mg I doubt how much was it working, but with 80mg it is going to work and you will see the result over the next 2 MRIs. I don't think that doing lumbar instead of ommaya does much difference.
Mario

02-15-2013, 10:14 AM	#120
marvass Senior Member Join Date: May 2012 Posts: 105	Re: Intrathecal (IT) Herceptin (Trastuzumab) for brain mets (Leptomeningeal Metastase But Carol's dose went up very quickly, if i remember correctly with the 14th dose we were already at 100mg, and MRI still showed more new spots inside the brain on the 2nd MRI after the 14th dose, then went to 150mg and after 22 weeks it just settled. With 40mg I doubt how much was it working, but with 80mg it is going to work and you will see the result over the next 2 MRIs. I don't think that doing lumbar instead of ommaya does much difference. Mario