|
Re: brain mets
Genentech is not supporting anything other than the Northwestern and Sloan Kettering work to determine whether IT Herceptin will hurt you at 10 mg, then 20 mg, then 30 mg, and finally 40 mg. They are not testing up to therapeutic dosing of 100 to 150 mg. MD Anderson wants to test at these dose ranges, but there is no drive by Genentech as they do not see the need. Off label treatment at the higher dosing still gets them drug to sell without paying for the high dose that is needed to be therapeutic. The drug does not get the brain and spine, that is why intrathecal treatment is needed. The drug metabolizes really fast in the spinal fluid, which is the reason for the high dose necessary. We pushed hard to have the cancer agree. I pulled every favor and every miracle I had to get Nina treated. I am trying to do the same for all the forum members that need the info, but my bag of tricks needs to be refilled. I am working on it. Nina is NED since October (really since April if you do not consider the two month's of "we don't know what this is" on the MRI scans). Time to help others.
Rolepaul (Superior is my new home town so should I change to SuperPaul?)
|