HER2 Support Group Forums - View Single Post - a large pooled analysis of benefit of herceptin beyond progression in Stage IVs

Rolepaul · 01-02-2013, 12:10 PM

The problem is that CSF has a high turnover and that the concentration seen in my Xeloda/Tykerb treated patient CSF was still less than 10% of the blood concentration. High concentrations were found to be needed in the CSF to be effective. This was also true with three other patients that are seeing some success with IT Herceptin.

01-02-2013, 12:10 PM	#2
Rolepaul Senior Member Join Date: Jan 2012 Location: Boulder Colorado as of January 2013 Posts: 391	Re: a large pooled analysis of benefit of herceptin beyond progression in Stage IVs The problem is that CSF has a high turnover and that the concentration seen in my Xeloda/Tykerb treated patient CSF was still less than 10% of the blood concentration. High concentrations were found to be needed in the CSF to be effective. This was also true with three other patients that are seeing some success with IT Herceptin.