HER2 Support Group Forums - View Single Post

chrisy · 01-01-2013, 07:11 PM

Schoonder is right as usual.

True, you never know for sure what will happen, but I do know from the "last time" this happened, it is unlikely that if you are already in the trial prior to the end date and if you are benefitting from TDM1, that they would kick you off the drug. It would be unethical. If it were me, I'd get on TDM1 as soon as you can if you have access to an EAP. That way you sort of have squatters rights.

By the way I love your blog. It's goals season right now at work and in my business peer group, and I find the entire thing a bit depressing. Maybe I'll see if I can get away with "Get up. Survive. Go back to bed" or something like that. Of course I doubt anyone would pay me to do that, but it would be good for a laugh.

Good luck with your treatment decisions...even and especially if you DON'T need to change at this time.

Chris

01-01-2013, 07:11 PM	#3
chrisy Senior Member Join Date: Sep 2005 Location: Central Coast, CA Posts: 3,207	Re: Question about TDM1 I don't understand Schoonder is right as usual. True, you never know for sure what will happen, but I do know from the "last time" this happened, it is unlikely that if you are already in the trial prior to the end date and if you are benefitting from TDM1, that they would kick you off the drug. It would be unethical. If it were me, I'd get on TDM1 as soon as you can if you have access to an EAP. That way you sort of have squatters rights. By the way I love your blog. It's goals season right now at work and in my business peer group, and I find the entire thing a bit depressing. Maybe I'll see if I can get away with "Get up. Survive. Go back to bed" or something like that. Of course I doubt anyone would pay me to do that, but it would be good for a laugh. Good luck with your treatment decisions...even and especially if you DON'T need to change at this time. Chris __________________ Chris in Scotts Valley June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?" 9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++ 10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response! 04/05 - 4/07 Herception every 3 wks, Continue NED 04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial 06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin 01/08 Progression in liver 02/08 Begin (TDM1) trial 08/08 NED! It's Working! Continue on TDM1 02/09 Continue NED 02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED 12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver 07/11 - 11/11 Herceptin/Xeloda -not working:( 12/11 Begin MM302 Phase I trial - bust:( 03/12 3rd times the charm? AKT trial 5/12 Scan shows reduction! 7/12 More reduction!!!! 8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!) 9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3 11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc 11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go. 2/13 Gemzar/Carbo/Herceptin - no go. 3/13 TACE procedure