HER2 Support Group Forums - View Single Post - exosomes responsible for establishing environment ripe for metastases

gdpawel · 12-21-2012, 03:22 PM

Yes, the exosomes are responsible for metastasis in other cancers as well. These exosome vesicles (small bubble within a cell) are a specific subtype of membrane vesicles that circulate in the blood and contain numerous proteins, lipids, and even nucleic acids.

This is the mechanism by which cancer cells release small exosome vesicles that travel to various locations in the body (brain, bone, liver, lungs), where the cellular material inside the vesicles fuses with these organs, establishing the perfect environment to spread tumor cells (metastasis).

The exosomes could potentially be advantageous in the diagnosis, prognosis and treatment of cancer, given that they are readily accessible and measurable as they circulate in the bloodstream.

12-21-2012, 03:22 PM	#3
gdpawel Senior Member Join Date: Aug 2006 Location: Pennsylvania Posts: 1,080	Re: exosomes responsible for establishing environment ripe for metastases Yes, the exosomes are responsible for metastasis in other cancers as well. These exosome vesicles (small bubble within a cell) are a specific subtype of membrane vesicles that circulate in the blood and contain numerous proteins, lipids, and even nucleic acids. This is the mechanism by which cancer cells release small exosome vesicles that travel to various locations in the body (brain, bone, liver, lungs), where the cellular material inside the vesicles fuses with these organs, establishing the perfect environment to spread tumor cells (metastasis). The exosomes could potentially be advantageous in the diagnosis, prognosis and treatment of cancer, given that they are readily accessible and measurable as they circulate in the bloodstream.