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Re: Keep existing treatment or get a second opinion?
Dear Jill,
We are all so different and bare statistics don't say much about each individual, so it is difficult to give advice. However, I think it's always worth getting a second opinion, even if only for peace of mind
I understand Herceptin doesn't cross the blood/brain barrier, unlike lapatinib, but there is something in sticking with a regime that is relatively gentle if it is keeping things stable, and keeping the "big guns" in reserve.
A chat with another doctor might help clarify your thinking.
Best wishes..... pam
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Diagnosed 2004: Lumpectomy - 2 tumours, both grade 1 infiltrating duct carcinoma, about 12mm. ER+,
C-erbB-2 status 3+.
Clear margins, no nodal involvement.
Radiotherapy, i year Tamoxifen, 4 years Arimidex.
Rediagnosed 2012: Multiple bone metastases.
3/12: began on Marianne trial - T-DM1 + Pertuzamab/Placebo.
5/12:Unexpected development of numerous bilateral liver mets. Came off trial.
Started Docetaxol/ Herceptin + Zometa.
8/12:Bones stable +major regression in liver (!)
9/12:Can't take any more Docetaxol! Start on Herceptin and Tamoxifen. Cross fingers!
Changed to Denosumab.
11/12: Scan shows stable - yay!
11/13: Still stable :-) !!!
1/16: All stable, but lowered calcium, so switched to Zometa 3 monthly.
2/19: Happily still stable on Herceptin, Letrozole and 3 monthly Zometa.
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