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Old 11-02-2012, 08:40 PM   #4
Mandamoo
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Join Date: Jul 2011
Location: Melbourne, Australia
Posts: 432
Re: Tumour gone after neo-adjuvant chemo?

That is wonderful that she had such a great response to the treatment and even better if she doesn't have spine met - I guess the only definitive way there is biopsy but I don't know how this works with bones - I have had some suspicious spots on bones that they have determined over scans are not cancer.
Re the surgery - seek varied opinions. I have a friend who had a complete response only to have recurrence back in the breast within months of completing her chemo - she was a Brca girl though and I think always planned the double mastectomy but was breast feeding. (She had chemo throughout her pregnancy)
I wish your daughter well and hope that it is not a met in her bones. Are her lymph nodes clear too?
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Amanda xx
40 year old Mum to three gorgeous kids - son 5 and daughters 8 and 11
Wife to my wonderfully supportive husband of 17 years!
22 February 2011 - Diagnosed Early Breast Cancer IDBC Stage2b (ER/PR -ve, Her2+ve +++) - 38 years old
(L) skin sparing mastectomy with tissue expander, axilla clearance (2/14 affected) clear margins.
Fec*3, Taxotere and herceptin*2 - stopped due to secondary diagnosis

June 24 2011 Stage IV - Skin met, axilla node, multiple lung lesions

Bolero3 trial - Navelbine, Hereptin weekly, daily Everolimus/Placebo
February 2012 - July 2012 Tykerb and Xeloda - skin mets resolved, Lungs initially dramatically reduced but growing again
August 2012 (turn 40!) tykerb and herceptin (denied compassionate use of TDM1) while holidaying in Italy!
September 2012 - January 2013 TDM1 as part of the Th3resa trial - lymph nodes resolved, lungs slowly progressing.
January 2013 - herceptin, carboplatin and Perjeta (compassionate access)
April 2013 - Some progression in lungs and lymph nodes - Abraxane, Herceptin and Perjeta
July 2013 - mixed response - dramatic reduction of most lung disease, progression of smaller lung nodules and cervical and hilar nodes - ? Add avastin.
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