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Re: TDM-1 side effects
I will be receiving my third dose of TDM1 tomorrow. I receive it every three weeks. So far the first two infusions did bring my platelets down. Had to have a blood transfusion after the second dose. I have experienced severe headaches after each infusion which I now take a low dose steroid and they are usually gone by the third day post infusion. I have had to have a periencentisis done two weeks ago as I was retaining too much fluid which has messed up my digestive system since that time. My abdomen and liver have been swollen, however this is the first week that the swelling has reduced. I'm thinking it may be working. Other than that I have good days and not so good days.
Angie
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Diagnosed Stage IV Breast Cancer in August 2011 Her2+ Er-pr-
Metastic to liver
8 rounds Abraxaine (3 weeks on 1 week off) and Herceptin (once weekly)
April 2012 stopped Abraxaine, Herceptin only every three weeks. (liver and breast tumors shrank considerably but not NED)
June 2012 CT scan showed enlarged axillary lymph node not responding. Biopsy of node revealed same cancer. Surgeon recommended breast MRI. MRI revealed new area in left breast 6mm. Breast biopsy revealed same cancer. Surgeon not sure if we should do surgery.
7/29/12 CT scan to see if spreading anywhere else. Awaiting results to determine plan of care. Will meet with oncologist 8/7/12
8/7/12 no progression in liver. No evidence of disease anywhere else. Dr recommending TDM1 trial in Nashville. Waiting.
9/18/12 Began TDM1 in Nashville. Hopeful!!
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