Re: Pl help:Failed perjetA, now TDM1?
I am at a research hospital at UCSD with a good team. My team of neuro and radiation onc recently completed six cycle of intrathecal chemo for my leptomenginal mets. They regularly scan my brain mets and are trying to push off radiation as far out possible since so far the mets are stable and asymptote attic. They are trying to conserve my QOL and want me to focus on controlling systemic disease. I am meeting my chielf oncologist this morning and will let you know what she suggests. TDM1 looks like the leading candidate but the concern is some other pathway has been dominant since Perjeta worked so well for six weeks and then stopped.
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