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Old 10-11-2012, 10:06 PM   #33
chrisy
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Join Date: Sep 2005
Location: Central Coast, CA
Posts: 3,207
Re: Perjeta - leap of faith

I got my second Perjeta infusion tuesday, And "yippee" some taxotere to boot. Just as I was getting some eyebrows. But, first priority is to regain control over the cancer and the chemo holiday caused by my surgical,issues wasn't much fun anyway.

Also had a scan monday which showed comtinued progression, I expected it would, having been basically untreated for a month and without chemo for nearly two. Tumor markers also shot up in the last three weeks so that has me worried but hopefully those too will head backin the right direction

The leg is healing well fortunately since we're gonna slow that down with chemo. But the wound vac is amazing, the suckers get smaller day by day and it may be good we might be able to discontinue that.

I even catch myself walkingoff withiout my crutches!
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Chris in Scotts Valley
June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial

5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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