[Lani]

don't know what you are referring to but there are lots of trials involving HDAC inhibitors aka histone deacetylase inhibitors

Histones are like overcoats covering the DNA when parts of it are acetylated they cause epigenetic changes ie either causing the underlying gene to be read or not read Depending on whether the underlying gene is a regular gene or an oncogene or a tumor suppressor gene, the results can be quite different!

Hope this helps!