HER2 Support Group Forums - View Single Post - Guinea Pig

rhondalea · 05-09-2012, 03:55 PM

Hi Jessica,

You can be sure I'll be posting myself silly if I start to have SEs. I'm such a whiner.

I hope your tummy clears up for you soon so you can restart. It really seems to have very high potential for such a simple drug.

Hi Rich,

Well, if I were to bypass the study and go straight to my endo, there would be no problem getting the brand name drug (and indeed, when given the option, I refuse generics, even when it means paying through the nose for the brand). But someone somewhere has to get the placebo, so I'm content to play the odds.

As for the hypoglycemia, I'm glad to hear that. I've got it pretty well under control now, but there was a time when it regularly knocked me for a loop. Eating properly helps a lot. Back when I had no idea what was going on, I self-medicated with Brach's cinnamon candies. They kept me upright, but my brain buzzed like a giant hive the entire time.

The trial is 5 years, according to the informed consent they sent me. I'll be done with tamoxifen before I'm done with this. Sheesh.

05-09-2012, 03:55 PM	#4
rhondalea Senior Member Join Date: Jun 2011 Location: Somerset, NJ Posts: 487	Re: Guinea Pig - Metformin Trial Hi Jessica, You can be sure I'll be posting myself silly if I start to have SEs. I'm such a whiner. I hope your tummy clears up for you soon so you can restart. It really seems to have very high potential for such a simple drug. Hi Rich, Well, if I were to bypass the study and go straight to my endo, there would be no problem getting the brand name drug (and indeed, when given the option, I refuse generics, even when it means paying through the nose for the brand). But someone somewhere has to get the placebo, so I'm content to play the odds. As for the hypoglycemia, I'm glad to hear that. I've got it pretty well under control now, but there was a time when it regularly knocked me for a loop. Eating properly helps a lot. Back when I had no idea what was going on, I self-medicated with Brach's cinnamon candies. They kept me upright, but my brain buzzed like a giant hive the entire time. The trial is 5 years, according to the informed consent they sent me. I'll be done with tamoxifen before I'm done with this. Sheesh. __________________ 2/6/09 Core needle biopsy: negative; Mammos through 2010: no change 3/30/11 Pea-sized lump in left breast at site of prior biopsy; mammo negative, sonogram not so much 4/14/11 Core needle biopsy: negative for cancer 5/18/11 Excisional biopsy 1.2 cm tumor, LVI, positive margin; ER+60%,PR+20%,HER2/CEP17 5 6/15/11 BMX: Left DCIS & LH; Right ADH; SNB: 2/3 nodes: 1.4 cm and 1 mm; ALND L1&2: 0/10; Stage IIa, Grade 3 7/14/11 CT/Bone scans NED; MUGA 66% 7/19/11 Biweekly dd AC w/Neulasta; done 8/30/11 9/13/11 Transfusion (Hemoglobin 8.6); MUGA 64% 9/20/11 Start Taxol + Herceptin; Taxol done 12/6/2011; continue Herceptin until 9/4/2012 12/27/11 Radiation - 6 weeks; 2/27/2012 - DONE! Yayyyy! 2/29/12 Start Tamoxifen 20 mg/day; continue until 2/28/17 5/16/12 Start five-years Metformin trial 6/19/12 MUGA 61% 8/21/12 Brain MRI NED (head still hurts, brain still fogged) 9/4/12 Herceptin done! 9/6/12 Port out! 7/11/13 Aricept 5mg for cognitive impairment; increased to 10mg as of 8/23/13; back to 5mg 12/2013 5/2014 Add Namenda 7mg 9/2014 Stop Aricept and Namenda; Neuropsychological evaluation 10/24/14 Start cognitive rehabilitation therapy