[chrisy]

Greg,

Phil said a lot. All true.

There are lots of options, and this should be a very exciting year for her2 agent approvals.

One word about trial stats....they represent data points over everyone in the trial. It is also the MEDIAN, half the people had pfs of less tha 4 months , half had longer pfs. The lower "half" includes people who did not respond at all, while the upper half usually includes responders who have much, much longer..

My point is, statistics do not reflect how any individual will respond. So don't get hung up on "this will only buy us 4 months". Picture yourself on the far right tail of the curve. If you have not read it, I highly recommend "the median is not the message". You can googl it easily

It's hard not to second guess and play "what if?". You just have to do the best you can to do the research, align yourself with a top cancer center (most local oncologists are happy to work and play with these top researchers) , fight for what you think is best, and make the best choices you can. Easy, huh?

But I really second Phil's recommendation of having a relationship with a top onc, at a top research hospital, with expertise in your situation. Phil's righ on in his comments there - they have access to all the research going on, even unreported stuff, and can offer many options that are not available except at a large research facility.

Hang in there.