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phil · 05-02-2012, 01:05 PM

Lots of wisdom inwhat kk1 is saying. hers another thought, if you are going to try tyk/ xel. anyway, why not take 2 out of 3 chance on getting t dm-1 , if you dont, your fallback is tyk./xel. Thats Theresa, its a big trial. If you look at its hx., and its "suspisciously unique " randomization of 2 to 3 , I think its the co's attempt to get as many on t dm-1 and still satisfy This FDA's forcing them to do trials . Most trials would have a 50/50 randomization, or maybe 3 ' arms ", . if my guess is corect, kudos to Genentech. They know, and we know that they have a breakthrough drug.
The main trial This FDA is forcing , EMILIA , is done, data will go to to FDA soon, next month ? Then This FDA typically will take 6 months to approve. It shows that t dm-1 is superior to tyk/xel. How superior ? I am betting a lot, in survivability, and in QOL. tyk/xel is notoriuos for dirrhea, and " hand/foot syndrome , my wife had it all, droppped 15 lbs off an already 4 yr battling thin frame, wore gloves w/ lotion to bed every night as her fingers cracked. Turned the palms of hands, soles of feet orange T dm-1 : platelets for some , that can be managed w forwarning , dose reduction.

05-02-2012, 01:05 PM	#29
phil Senior Member Join Date: Nov 2010 Posts: 393	Re: Treatment Question Lots of wisdom inwhat kk1 is saying. hers another thought, if you are going to try tyk/ xel. anyway, why not take 2 out of 3 chance on getting t dm-1 , if you dont, your fallback is tyk./xel. Thats Theresa, its a big trial. If you look at its hx., and its "suspisciously unique " randomization of 2 to 3 , I think its the co's attempt to get as many on t dm-1 and still satisfy This FDA's forcing them to do trials . Most trials would have a 50/50 randomization, or maybe 3 ' arms ", . if my guess is corect, kudos to Genentech. They know, and we know that they have a breakthrough drug. The main trial This FDA is forcing , EMILIA , is done, data will go to to FDA soon, next month ? Then This FDA typically will take 6 months to approve. It shows that t dm-1 is superior to tyk/xel. How superior ? I am betting a lot, in survivability, and in QOL. tyk/xel is notoriuos for dirrhea, and " hand/foot syndrome , my wife had it all, droppped 15 lbs off an already 4 yr battling thin frame, wore gloves w/ lotion to bed every night as her fingers cracked. Turned the palms of hands, soles of feet orange T dm-1 : platelets for some , that can be managed w forwarning , dose reduction.