[Debbie L.]

Jane, I can't answer your question, but I'm curious why you want to avoid Tamoxifen.

You probably know that both oophorectomy and AIs increase risk of osteoporosis. I think AIs are the bigger culprit. I haven't seen anything to say that AIs in the absence of ovaries cause more osteoporosis than is seen in a naturally-menopausal woman (but that doesn't mean it's not out there).

Debbie Laxague