Perhaps teh two states are anabolic and catabolic. Maybe existing drugs can address both: Metformin and Chloroquine
http://www.ncbi.nlm.nih.gov/pmc/arti...7/?tool=pubmed
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Uncoupling parasitic cancer metabolism. Drugs such as chloroquine (which inhibits autophagy) and metformin (which inhibits lipolysis), will prevent energy transfer to cancer cells and tumor growth.
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the anticancer activity of metformin may stem from its antimitochondrial activity, thereby preventing cancer cells from using the energy-rich onco-metabolites (L-lacate, ketones, glutamine and fatty acids) derived from the tumor stroma.
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