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Mandamoo · 12-26-2011, 03:08 PM

Hi Deena I live in Australia so can't help with the insurance question - sorry. Was it significant progression? I have been on everolimus, navelbine and herceptin for 6 months now - my first scan showed regression but all scans since have been stable or slight progression. Several radiologists have viewed and say it is all just stable from the start (mets are multiple and largest is 8mm most are under 4mm) - they can vary mm or two up or down from scan to scan. My onc adopts a sit and see unless progression is significant. I am just wondering if it is too early to jump ship?
Also wondering if having had navelbine precludes you from Bolero trials? Of course you risk getting placebo too.
I wish you the best in finding a solution.

12-26-2011, 03:08 PM	#4
Mandamoo Senior Member Join Date: Jul 2011 Location: Melbourne, Australia Posts: 432	Re: I could really use some input Hi Deena I live in Australia so can't help with the insurance question - sorry. Was it significant progression? I have been on everolimus, navelbine and herceptin for 6 months now - my first scan showed regression but all scans since have been stable or slight progression. Several radiologists have viewed and say it is all just stable from the start (mets are multiple and largest is 8mm most are under 4mm) - they can vary mm or two up or down from scan to scan. My onc adopts a sit and see unless progression is significant. I am just wondering if it is too early to jump ship? Also wondering if having had navelbine precludes you from Bolero trials? Of course you risk getting placebo too. I wish you the best in finding a solution. __________________ Amanda xx 40 year old Mum to three gorgeous kids - son 5 and daughters 8 and 11 Wife to my wonderfully supportive husband of 17 years! 22 February 2011 - Diagnosed Early Breast Cancer IDBC Stage2b (ER/PR -ve, Her2+ve +++) - 38 years old (L) skin sparing mastectomy with tissue expander, axilla clearance (2/14 affected) clear margins. Fec3, Taxotere and herceptin2 - stopped due to secondary diagnosis June 24 2011 Stage IV - Skin met, axilla node, multiple lung lesions Bolero3 trial - Navelbine, Hereptin weekly, daily Everolimus/Placebo February 2012 - July 2012 Tykerb and Xeloda - skin mets resolved, Lungs initially dramatically reduced but growing again August 2012 (turn 40!) tykerb and herceptin (denied compassionate use of TDM1) while holidaying in Italy! September 2012 - January 2013 TDM1 as part of the Th3resa trial - lymph nodes resolved, lungs slowly progressing. January 2013 - herceptin, carboplatin and Perjeta (compassionate access) April 2013 - Some progression in lungs and lymph nodes - Abraxane, Herceptin and Perjeta July 2013 - mixed response - dramatic reduction of most lung disease, progression of smaller lung nodules and cervical and hilar nodes - ? Add avastin. Last edited by Mandamoo; 12-26-2011 at 03:11 PM.. Reason: iPhone edits!