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Re: Thyroid desease and breast cancer
I am planning to start posting again soon (really), and I will definitely follow-up this thread because I am quite sure that thyroid has an enormous impact on breast cancer. In the meantime, here are a few of the (somewhat conflicting) links I've collected since I concluded that too much exogenous T3 (i.e., Armour and Cytomel) was the cause of my cancer:
Effects of thyroid hormones on human breast cancer cell proliferation
http://www.ncbi.nlm.nih.gov/pubmed/18328691
Prospectively measured triiodothyronine levels are positively associated with breast cancer risk in postmenopausal women
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917028/
Hypothyroidism Enhances Tumor Invasiveness and Metastasis Development
http://www.plosone.org/article/info:...l.pone.0006428
Hypothyroxinemia as a goal in cancer management by triiodothyronine (T3) substitution for supplemental L-thyroxine (T4) and T3 modulated hypothyroxinemia
http://www.asco.org/ascov2/Meetings/...stractID=83728
I have more but the data is on my other computer (which isn't functional at the moment). I also have data that makes a connection between thyroid issues and prostate cancer.
As soon as I have a grip, I'll add to this.
rl
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2/6/09 Core needle biopsy: negative; Mammos through 2010: no change
3/30/11 Pea-sized lump in left breast at site of prior biopsy; mammo negative, sonogram not so much
4/14/11 Core needle biopsy: negative for cancer
5/18/11 Excisional biopsy 1.2 cm tumor, LVI, positive margin; ER+60%,PR+20%,HER2/CEP17 5
6/15/11 BMX: Left DCIS & LH; Right ADH; SNB: 2/3 nodes: 1.4 cm and 1 mm; ALND L1&2: 0/10; Stage IIa, Grade 3
7/14/11 CT/Bone scans NED; MUGA 66%
7/19/11 Biweekly dd AC w/Neulasta; done 8/30/11
9/13/11 Transfusion (Hemoglobin 8.6); MUGA 64%
9/20/11 Start Taxol + Herceptin; Taxol done 12/6/2011; continue Herceptin until 9/4/2012
12/27/11 Radiation - 6 weeks; 2/27/2012 - DONE! Yayyyy!
2/29/12 Start Tamoxifen 20 mg/day; continue until 2/28/17
5/16/12 Start five-years Metformin trial
6/19/12 MUGA 61%
8/21/12 Brain MRI NED (head still hurts, brain still fogged)
9/4/12 Herceptin done!
9/6/12 Port out!
7/11/13 Aricept 5mg for cognitive impairment; increased to 10mg as of 8/23/13; back to 5mg 12/2013
5/2014 Add Namenda 7mg
9/2014 Stop Aricept and Namenda; Neuropsychological evaluation
10/24/14 Start cognitive rehabilitation therapy
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