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Lori R · 12-01-2011, 06:48 AM

Debbie,
Thank you for starting this thread. I am very anxious to hear about the status of Pertuzumab. My onc has expressed excitement about this possibility, yet when I try to gain insights she doesn't seem to have many specifics for me.

Chrisy and all attending SABCS...thank you so much for going. It would be great if you guys could get the scoop on FDA approval status. My internet searches indicated that back in the summer and fall things were moving forward for approval. Then all goes radio silent. So if you could get a sense of timing that would be great!!

OK...getting greedy here.....the only trials I saw paired Pertuzumab with Doxil. I had hoped for a very targeted option of Herceptin + Pertuzumab. It would be wonderful if you could get a sense of what the potential cocktail might look like.

Exciting stuff for sure and as everyone knows, looking for another option for my hip pocket.

Again, thank you to all your brainiacs attending SABCS. I am thrilled to have the inside track on these options. My onc has come to respect my insights based on all I learn from this site.

12-01-2011, 06:48 AM	#4
Lori R Senior Member Join Date: Jan 2008 Location: Evergreen, Colorado Posts: 454	Re: Experience with Pertuzumab? Debbie, Thank you for starting this thread. I am very anxious to hear about the status of Pertuzumab. My onc has expressed excitement about this possibility, yet when I try to gain insights she doesn't seem to have many specifics for me. Chrisy and all attending SABCS...thank you so much for going. It would be great if you guys could get the scoop on FDA approval status. My internet searches indicated that back in the summer and fall things were moving forward for approval. Then all goes radio silent. So if you could get a sense of timing that would be great!! OK...getting greedy here.....the only trials I saw paired Pertuzumab with Doxil. I had hoped for a very targeted option of Herceptin + Pertuzumab. It would be wonderful if you could get a sense of what the potential cocktail might look like. Exciting stuff for sure and as everyone knows, looking for another option for my hip pocket. Again, thank you to all your brainiacs attending SABCS. I am thrilled to have the inside track on these options. My onc has come to respect my insights based on all I learn from this site. __________________ 2007 Oct - Diagnosed - Stage IV 5 c.m. IDC - Left Side er/pr- Her2+++ Node + 2/14 - Single Liver Met Double Mastectomy Nov - Begin T+H 2008 Feb-Complete 6 cycles- T&H- NED March - Continue - Herceptin Only April - Rads for 6 weeks 2009 Continue Herceptin - Continue NED April - Recurrance- 3 cm. Liver Met May - Cryosurgery June - November - Abraxane + Herceptin Aug - PET/CT - CTC = 0 Back to NED 2010 January - Continue NED July - Recurrance - 3 cm Liver Met CTC=1 August - Cryosurgery #2 August - November Navelbine November - Back to NED - End Navelbine 2011 Feb - Recur - 4 cm Liver Met - Same Left Lobe March Surgery it is -Couldn't get a clean margin July - Confirmed continued liver involvement August - Begin Herceptin + Tykerb October - Mixed results from H+T Add Abraxane + H + T - Nov - April 2012 January PET Scan - It's working!! April - Back to NED July - Recurrance August - Begin TDM-1 Trial (Taxol + TDM-1)