HER2 Support Group Forums - View Single Post - for Stage IVs running out of options, a vaccine trial with hopeful results

Rich66 · 11-10-2011, 03:22 PM

from above excerpt: "multiple randomized studies have shown an improved overall survival without initial improved time to progression,"

So..could it be possible that some of these "failed" vaccines would yield better results if continued past progression? It seems the RECIST (near term shrinkage etc) criteria may not be up to the task of evaluating immune based therapies.

11-10-2011, 03:22 PM	#4
Rich66 Senior Member Join Date: Feb 2008 Location: South East Wisconsin Posts: 3,431	Re: for Stage IVs running out of options, a vaccine trial with hopeful results from above excerpt: "multiple randomized studies have shown an improved overall survival without initial improved time to progression," So..could it be possible that some of these "failed" vaccines would yield better results if continued past progression? It seems the RECIST (near term shrinkage etc) criteria may not be up to the task of evaluating immune based therapies.