HER2 Support Group Forums - View Single Post - The traditional diet of Greece and cancer.

R.B. · 10-25-2011, 04:09 PM

This is neat because it relates the Omega 3:6 profile of strictly controlled diet to what is happening in prostate cancer cells in living humans. The diet was tested in the time frame whilst patients were awaiting surgical removal of cancerous tissue, which tissue was then available for examination as to the effect of the different diets on cancer cell fat composition, structure, cell division rate, etc. The trial is small but has prompted a bigger trial

http://www.newswise.com/articles/you...e-cancer-cells

You are What You Eat: Low-Fat Diet with Fish Oil Slowed Growth of Human Prostate Cancer Cells
Released: 10/25/2011 7:00 AM EDT
Source: University of California, Los Angeles (UCLA), Health Sciences

"Newswise — A low-fat diet with fish oil supplements eaten for four to six weeks prior to prostate removal slowed down the growth of prostate cancer cells – the number of rapidly dividing cells – in human prostate cancer tissue compared to a traditional, high-fat Western diet.

Done by researchers at UCLA’s Jonsson Comprehensive Cancer Center, the short-term study also found that the men on the low-fat, fish oil supplement diet were able to change the composition of their cell membranes in both the healthy cells and the cancer cells in the prostate. They had increased levels of omega-3 fatty acids from fish oil and decreased levels of omega-6 fatty acids from corn oil in the cell membranes, which may directly affect the biology of the cells, though further studies are needed, said Dr. William Aronson, the study’s first author and a researcher with UCLA’s Jonsson Comprehensive Cancer Center.

The study also found that blood obtained from patients after the low-fat, fish oil diet program slowed the growth of prostate cancer cells in a test tube as compared to blood from men on the Western diet, which did not slow cancer growth.

“The finding that the low-fat, fish oil diet reduced the number of rapidly dividing cells in the prostate cancer tissue is important because the rate at which the cells are dividing can be predictive of future cancer progression,” Aronson said. “The lower the rate of proliferation, the lesser the chances that the cancer will spread outside the prostate, where it is much harder to treat.” . . .

"- the “treatment” was indeed reaching the targeted organ because of the changes in the prostate cell membrane’s fatty acid composition." . . .

"Diet studies often are difficult to evaluate because getting patients to comply with dietary changes can be challenging. However, the food eaten by men in both arms of this study was precisely controlled, Aronson said. The meals were prepared by chefs in the UCLA Clinical Translational Research Center and delivered in bulk to study participants several times a week. Participants also met with a dietician, kept food diaries and were required to return uneaten food."

"
The study appeared Oct. 25, 2011 in Cancer Prevention Research, a peer-reviewed journal of the American Association for Cancer Research."

10-25-2011, 04:09 PM	#13
R.B. Senior Member Join Date: Mar 2006 Posts: 1,843	Re: The traditional diet of Greece and cancer. This is neat because it relates the Omega 3:6 profile of strictly controlled diet to what is happening in prostate cancer cells in living humans. The diet was tested in the time frame whilst patients were awaiting surgical removal of cancerous tissue, which tissue was then available for examination as to the effect of the different diets on cancer cell fat composition, structure, cell division rate, etc. The trial is small but has prompted a bigger trial http://www.newswise.com/articles/you...e-cancer-cells You are What You Eat: Low-Fat Diet with Fish Oil Slowed Growth of Human Prostate Cancer Cells Released: 10/25/2011 7:00 AM EDT Source: University of California, Los Angeles (UCLA), Health Sciences "Newswise — A low-fat diet with fish oil supplements eaten for four to six weeks prior to prostate removal slowed down the growth of prostate cancer cells – the number of rapidly dividing cells – in human prostate cancer tissue compared to a traditional, high-fat Western diet. Done by researchers at UCLA’s Jonsson Comprehensive Cancer Center, the short-term study also found that the men on the low-fat, fish oil supplement diet were able to change the composition of their cell membranes in both the healthy cells and the cancer cells in the prostate. They had increased levels of omega-3 fatty acids from fish oil and decreased levels of omega-6 fatty acids from corn oil in the cell membranes, which may directly affect the biology of the cells, though further studies are needed, said Dr. William Aronson, the study’s first author and a researcher with UCLA’s Jonsson Comprehensive Cancer Center. The study also found that blood obtained from patients after the low-fat, fish oil diet program slowed the growth of prostate cancer cells in a test tube as compared to blood from men on the Western diet, which did not slow cancer growth. “The finding that the low-fat, fish oil diet reduced the number of rapidly dividing cells in the prostate cancer tissue is important because the rate at which the cells are dividing can be predictive of future cancer progression,” Aronson said. “The lower the rate of proliferation, the lesser the chances that the cancer will spread outside the prostate, where it is much harder to treat.” . . . "- the “treatment” was indeed reaching the targeted organ because of the changes in the prostate cell membrane’s fatty acid composition." . . . "Diet studies often are difficult to evaluate because getting patients to comply with dietary changes can be challenging. However, the food eaten by men in both arms of this study was precisely controlled, Aronson said. The meals were prepared by chefs in the UCLA Clinical Translational Research Center and delivered in bulk to study participants several times a week. Participants also met with a dietician, kept food diaries and were required to return uneaten food." " The study appeared Oct. 25, 2011 in Cancer Prevention Research, a peer-reviewed journal of the American Association for Cancer Research." Last edited by R.B.; 10-25-2011 at 04:35 PM..