HER2 Support Group Forums - View Single Post - lapatinib hepatoxicity investigated (article by the drug co. that makes it)

Rich66 · 10-05-2011, 10:01 AM

pibikay,
I think liver function tests are pretty important when liver mets are present, regardless of the treatment.

Lani,
Do you have access to the full article? I was just wondering how toxicity was defined in the paper.

Anecdotally, seems like most patients have no issue with Tykerb and liver function. But when it happens, seems to be pretty pronounced and the drug is stopped.

10-05-2011, 10:01 AM	#6
Rich66 Senior Member Join Date: Feb 2008 Location: South East Wisconsin Posts: 3,431	Re: lapatinib hepatoxicity investigated (article by the drug co. that makes it) pibikay, I think liver function tests are pretty important when liver mets are present, regardless of the treatment. Lani, Do you have access to the full article? I was just wondering how toxicity was defined in the paper. Anecdotally, seems like most patients have no issue with Tykerb and liver function. But when it happens, seems to be pretty pronounced and the drug is stopped.