HER2 Support Group Forums - View Single Post - metformin (common anti diabetes drug) decreases her2 protein levels by 85%

SarahFoodforBC · 08-16-2011, 02:35 PM

Another side of the metformin discussion is that type 2 diabetes has been shown to promote HER2+ tumor development. Keeping blood sugar under good control and avoiding insulin spikes (from carb-heavy meals) is important to help avoid a recurrence. Below is a recent study on HER2 and breast cancer (Google the title if you are interested).

"Diabetes mellitus accelerates ErbB2-induced breast carcinogenesis and shortens the survival of a mouse model of breast cancer and diabetes"

08-16-2011, 02:35 PM	#22
SarahFoodforBC Member Join Date: Feb 2010 Posts: 8	Re: metformin (common anti diabetes drug) decreases her2 protein levels by 85% Another side of the metformin discussion is that type 2 diabetes has been shown to promote HER2+ tumor development. Keeping blood sugar under good control and avoiding insulin spikes (from carb-heavy meals) is important to help avoid a recurrence. Below is a recent study on HER2 and breast cancer (Google the title if you are interested). "Diabetes mellitus accelerates ErbB2-induced breast carcinogenesis and shortens the survival of a mouse model of breast cancer and diabetes"