HER2 Support Group Forums - View Single Post - new drug being developed with an exciting combination of attributes !!

Lani · 04-21-2011, 11:41 AM

Estrogen receptor alpha

There are two kinds of estrogen receptors ERalpha and ER beta(actually there are more but they act more in the cytoplasm than the nucleus)

In any case ER beta confers a good prognosis to ER+ bc, ER alpha is the typical ER which usually responds to tamoxifen or AIs (through estrogen deprivation)

I haven't seen any pathologists' reports comment on ERbeta and believe only researchers are looking at it for now.

04-21-2011, 11:41 AM	#4
Lani Senior Member Join Date: Mar 2006 Posts: 4,783	Re: new drug being developed with an exciting combination of attributes !! Estrogen receptor alpha There are two kinds of estrogen receptors ERalpha and ER beta(actually there are more but they act more in the cytoplasm than the nucleus) In any case ER beta confers a good prognosis to ER+ bc, ER alpha is the typical ER which usually responds to tamoxifen or AIs (through estrogen deprivation) I haven't seen any pathologists' reports comment on ERbeta and believe only researchers are looking at it for now.