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Re: adding Src inhibitor 2 herceptin reverses resistance due 2 PTEN loss,IGFR1,EGFR,h
It is a good news/bad news sort of thing I guess
The bad news--her2+ breast cancer is more aggressive than most other kinds
The good news--they are much more advanced in knowing what drives her2+ breast cancer and developing drugs against it
What I liked about this article is that this drug targets many of the paths by which her2+ bc escapes from herceptin treatment when it becomes resistant or is de novo (right from the start) resistant ie, IGFR1, PTEN loss, EGFR, MET
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