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Old 01-30-2011, 06:03 PM   #6
Sheila
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Join Date: Aug 2003
Location: Morris, IL
Posts: 3,507
Re: resection of bc mets to liver prolongs survival in ER+ chemosensitive patients

This is very interesting to me as my dear friend who was diagnosed almost 4 years ago, Her2- ER+ and PR- was told today that she has reached the end of the road...she developed ascites 3 weeks ago, up until then was doing well on Navelbine, but no AI's. I think I diagnosed the ascites before her oncologist, they kept saying colon....I felt disease progression...she had a paracentesis 1 week ago, another 2 days ago and her abdiomen is already filled again. She was switched to Carbo/Gemzar, but it is playing havoc with her counts...now her Bili is going up dramatically.... her B/P is plumetting...she was discharged today from a large hospital in Chicago...I am amazed at how far she has gone down hill in 3 weeks...I just cannot lose another friend right now....I asked her why they never mentioned liver resection or ablation and she said numerous tumors...she went from working full time 3 weeks ago to this point...i am devastated any advice on what if anything I can do to help her? Her oncologist is a top onc. in Chicago at a well known hospital, and I fear she is too ill right now to seek another opinion.
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Hugs & Blessings
Sheila
Diagnosed at age 49.99999 2/21/2002 via Mammography (Calcifications)
Core Biopsy 2/22/02
L. Mastectomy 2/25/2002
Stage 1, 0.7cm IDC, Node Neg from 19 nodes Her2+++ ER PR Neg
6/2003 Reconstruction W/ Tissue Expander, Silicone Implant
9/2003 Stage IV with Mets to Supraclavicular nodes
9/2003 Began Herceptin every 3 weeks
3/2006 Xeloda 2500mg/Herceptin for recurrence to neck nodes
3/2007 Added back the Xeloda with Herceptin for continued mets to nodes
5/2007 Taken Off Xeloda, no longer working
6/14/07 Taxol/Herceptin/Avastin
3/26 - 5/28/08 Taxol Holiday Whopeeeeeeeee
5/29 2008 Back on Taxol w Herceptin q 2 weeks
4/2009 Progression on Taxol & Paralyzed L Vocal Cord from Nodes Pressing on Nerve
5/2009 Begin Rx with Navelbine/Herceptin
11/09 Progression on Navelbine
Fought for and started Tykerb/Herceptin...nodes are melting!!!!!
2/2010 Back to Avastin/Herceptin
5/2010 Switched to Metronomic Chemo with Herceptin...Cytoxan and Methotrexate
Pericardial Window Surgery to Drain Pericardial Effusion
7/2010 Back to walking a mile a day...YEAH!!!!
9/2010 Nodes are back with a vengence in neck
Qualified for TDM-1 EAP
10/6/10 Begin my miracle drug, TDM-1
Mixed response, shrinking internal nodes, progression skin mets after 3 treatments
12/6/10 Started Halaven (Eribulen) /Herceptin excellent results in 2 treatments
2/2011 I CELEBRATE my 9 YEAR MARK!!!!!!!!!!!!!
7/5/11 begin Gemzar /Herceptin for node progression
2/8/2012 Gemzar stopped, Continue Herceptin
2/20/2012 Begin Tomo Radiation to Neck Nodes
2/21/2012 I CELEBRATE 10 YEARS
5/12/2012 BeganTaxotere/ Herceptin is my next miracle for new node progression
6/28/12 Stopped Taxotere due to pregression, Started Perjeta/Herceptin
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