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Old 01-12-2011, 12:20 PM   #5
Joan M
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Join Date: Oct 2007
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Re: Time for a chemo break?

Laurie,

I would agree with Lori and Michka about the RFA and the cryoablation alternative. It would be best to speak directly to an interventional radiologist. That is the doctor who performs these procedures, and they would know whether it can be done. Avoid asking a surgeon. Many of them feel that these procedures are not worthwhile and plug surgery.

A second opinion is good. A had a lung RFA. The first doctor said the lesion was in an awkward place, but the second one said he had enough room and did the procedure.

RFAs and cryoablation are preformed frequently in the liver for both primary and secondary lesions. A lung RFA is a newer procedure.

Joan
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Diagnosed stage 2b in July 2003 (2.3 cm, HER2+, ER-/PR-, 7+ nodes). Treated with mastectomy (with immediate DIEP flap reconstruction), AC + T/Herceptin (off label). Cancer advanced to lung in Jan. 2007 (1 cm nodule). Started Herceptin every 3 weeks. Lung wedge resection April 2007. Cancer recurred in lung April 2008. RFA of lung in August 2008. 2nd annual brain MRI in Oct. 2008 discovered 2.6 cm cystic tumor in left frontal lobe. Craniotomy Oct. 2008 (ER-/PR-/HER2-) followed by targeted radiation (IMRT). Coughing up blood Feb. 2009. Thoractomy July 2009 to cut out fungal ball of common soil fungus (aspergillus) that grew in the RFA cavity (most likely inhaled while gardening). No cancer, only fungus. Removal of tiny melanoma from upper left arm, plus sentinel lymph node biopsy in Feb. 2016. Guardant Health liquid biopsy in Feb. 2016 showed mutations in 4 subtypes of TP53. Repeat of Guardant Health biopsy in Jana. 2021 showed 3 TP53 mutations, BRCA1 mutation and CHEK2 mutation. Invitae genetic testing showed negative for all of these. Living with MBC since 2007. Stopped Herceptin Hylecta (injection) treatment in March 2020. Recent 2023 annual CT of chest, abdomen and pelvis and annual brain MRI showed NED. Praying for NED forever!!
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